2-Aminopropanol → HCID 18382927, compound

HRID 2297787Notes

Reaction equation

HRID 2297787 reaction equation
[NH2:1][CH:2]([CH3:5])[CH2:3][OH:4].[NH:6]1[C:14]2[C:9](=[CH:10][C:11]([NH:15][C:16]3[C:17]4[S:24][C:23]([C:25]5[CH:32]=[CH:31][C:28]([CH:29]=O)=[CH:27][CH:26]=5)=[CH:22][C:18]=4[N:19]=[CH:20][N:21]=3)=[CH:12][CH:13]=2)[CH:8]=[CH:7]1>>[NH:6]1[C:14]2[C:9](=[CH:10][C:11]([NH:15][C:16]3[C:17]4[S:24][C:23]([C:25]5[CH:32]=[CH:31][C:28]([CH2:29][NH:1][CH:2]([CH3:5])[CH2:3][OH:4])=[CH:27][CH:26]=5)=[CH:22][C:18]=4[N:19]=[CH:20][N:21]=3)=[CH:12][CH:13]=2)[CH:8]=[CH:7]1

Participants

3

Reactant 2

HCID 51262-AminopropanolHCID 183827594-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde

Product 1

HCID 18382927HCID 18382927, compound

Procedure

The title compound was prepared from 2-amino-propan-1-ol and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by a procedure analogous to example 17. M.P. 160-175° C.; LC-MS: 444 (MH+); HPLC RT: 3.90 minutes.

Sources & evidence

ORD record
ord-c1e7a40795664f7faf3cb23402dec981
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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