2-(Methoxymethyl)pyrrolidine → HCID 18382981, compound

HRID 2297788Notes

Reaction equation

HRID 2297788 reaction equation
[CH3:1][O:2][CH2:3][CH:4]1[CH2:8][CH2:7][CH2:6][NH:5]1.[NH:9]1[C:17]2[C:12](=[CH:13][C:14]([NH:18][C:19]3[C:20]4[S:27][C:26]([C:28]5[CH:35]=[CH:34][C:31]([CH:32]=O)=[CH:30][CH:29]=5)=[CH:25][C:21]=4[N:22]=[CH:23][N:24]=3)=[CH:15][CH:16]=2)[CH:11]=[CH:10]1>>[NH:9]1[C:17]2[C:12](=[CH:13][C:14]([NH:18][C:19]3[C:20]4[S:27][C:26]([C:28]5[CH:35]=[CH:34][C:31]([CH2:32][N:5]6[CH2:6][CH2:7][CH2:8][CH:4]6[CH2:3][O:2][CH3:1])=[CH:30][CH:29]=5)=[CH:25][C:21]=4[N:22]=[CH:23][N:24]=3)=[CH:15][CH:16]=2)[CH:11]=[CH:10]1

Participants

3

Reactant 2

HCID 1439532-(Methoxymethyl)pyrrolidineHCID 183827594-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde

Product 1

HCID 18382981HCID 18382981, compound

Procedure

The title compound was prepared from 2-methoxymethyl-pyrrolidine and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by a procedure analogous to example 17. M.P. 161-177° C.; LC-MS: 470 (MH+); HPLC RT: 4.55 minutes.

Sources & evidence

ORD record
ord-2a3f40d835e54fbbbe75e28163ac8dbc
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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