N-(2-aminoethyl)acetamide → HCID 18382946, compound

HRID 2297789Notes

Reaction equation

HRID 2297789 reaction equation
[NH2:1][CH2:2][CH2:3][NH:4][C:5](=[O:7])[CH3:6].[NH:8]1[C:16]2[C:11](=[CH:12][C:13]([NH:17][C:18]3[C:19]4[S:26][C:25]([C:27]5[CH:34]=[CH:33][C:30]([CH:31]=O)=[CH:29][CH:28]=5)=[CH:24][C:20]=4[N:21]=[CH:22][N:23]=3)=[CH:14][CH:15]=2)[CH:10]=[CH:9]1>>[NH:8]1[C:16]2[C:11](=[CH:12][C:13]([NH:17][C:18]3[C:19]4[S:26][C:25]([C:27]5[CH:34]=[CH:33][C:30]([CH2:31][NH:1][CH2:2][CH2:3][NH:4][C:5](=[O:7])[CH3:6])=[CH:29][CH:28]=5)=[CH:24][C:20]=4[N:21]=[CH:22][N:23]=3)=[CH:14][CH:15]=2)[CH:10]=[CH:9]1

Participants

3

Reactant 2

HCID 66082N-(2-aminoethyl)acetamideHCID 183827594-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde

Product 1

HCID 18382946HCID 18382946, compound

Procedure

The title compound was prepared from N-(2-amino-ethyl)-acetamide and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by a procedure analogous to example 17. M.P. 142-155° C.; LC-MS: 457 (MH+); HPLC RT: 3.35 minutes.

Sources & evidence

ORD record
ord-4c46153500244262a798c26050da10cc
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

Loading…