7-(Diethylamino)-2-oxo-2H-chromene-3-carbaldehyde → 1-(5-carboxy-pentyl)-4-[(E)-2-(7-diethylamino-2-oxo-2H-chromen-3-yl)-vinyl]-6-sulfo-chinolinium betaine
Reaction equation
[CH2:1]([N:3]([CH2:17][CH3:18])[C:4]1[CH:13]=[C:12]2[C:7]([CH:8]=[C:9]([CH:15]=O)[C:10](=[O:14])[O:11]2)=[CH:6][CH:5]=1)[CH3:2].[C:19]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][N+:27]1[C:36]2[C:31](=[CH:32][C:33]([S:37]([O-:40])(=[O:39])=[O:38])=[CH:34][CH:35]=2)[C:30]([CH3:41])=[CH:29][CH:28]=1)([OH:21])=[O:20].[CH3:42][N+:43]([CH2:46][C:47]([OH:49])=[O:48])([CH3:45])[CH3:44]>CO.O>[C:19]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][N+:27]1[C:36]2[C:31](=[CH:32][C:33]([S:37]([OH:40])(=[O:39])=[O:38])=[CH:34][CH:35]=2)[C:30](/[CH:41]=[CH:15]/[C:9]2[C:10](=[O:14])[O:11][C:12]3[C:7]([CH:8]=2)=[CH:6][CH:5]=[C:4]([N:3]([CH2:17][CH3:18])[CH2:1][CH3:2])[CH:13]=3)=[CH:29][CH:28]=1)([OH:21])=[O:20].[CH3:42][N+:43]([CH2:46][C:47]([OH:49])=[O:48])([CH3:45])[CH3:44]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
0.2 mmol 7-diethylamino-2-oxo-2H-chromene-3-carbaldehyde and 0.2 mmol 1-(5-carboxy-pentyl)-4-methyl-6-sulfonato-chinolinium betaine are converted according to the general directions given above. Column chromatography: SiO2 (RP 18), eluent: methanol/water.
Sources & evidence
- ORD record
- ord-ef5b89c3f6384f20afb9e0e083ac7176
- Source dataset
- uspto-grants-2009_07
- Patent number
- US07563907B2
Reaction notes
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