4-Piperidinecarboxamide → HCID 44316797, compound

HRID 2297790Notes

Reaction equation

HRID 2297790 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]([NH2:9])=[O:8])[CH2:3][CH2:2]1.[NH:10]1[C:18]2[C:13](=[CH:14][C:15]([NH:19][C:20]3[C:21]4[S:28][C:27]([C:29]5[CH:36]=[CH:35][C:32]([CH:33]=O)=[CH:31][CH:30]=5)=[CH:26][C:22]=4[N:23]=[CH:24][N:25]=3)=[CH:16][CH:17]=2)[CH:12]=[CH:11]1>>[NH:10]1[C:18]2[C:13](=[CH:14][C:15]([NH:19][C:20]3[C:21]4[S:28][C:27]([C:29]5[CH:36]=[CH:35][C:32]([CH2:33][N:1]6[CH2:6][CH2:5][CH:4]([C:7]([NH2:9])=[O:8])[CH2:3][CH2:2]6)=[CH:31][CH:30]=5)=[CH:26][C:22]=4[N:23]=[CH:24][N:25]=3)=[CH:16][CH:17]=2)[CH:12]=[CH:11]1

Participants

3

Reactant 2

HCID 37724-PiperidinecarboxamideHCID 183827594-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde

Product 1

HCID 44316797HCID 44316797, compound

Procedure

The title compound was prepared from piperidine-4-carboxylic acid amide and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by a procedure analogous to example 17. M.P. 198-205° C.; LC-MS: 483 (MH+); HPLC RT: 3.56 minutes.

Sources & evidence

ORD record
ord-fa85b4cfd27c4633a637895b1359029a
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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