Ethanolamine → 2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzylamino}-ethanol

HRID 2297802Notes

Reaction equation

HRID 2297802 reaction equation
[NH2:1][CH2:2][CH2:3][OH:4].[NH:5]1[C:13]2[C:8](=[CH:9][C:10]([NH:14][C:15]3[CH:20]=[CH:19][N:18]=[C:17]4[CH:21]=[C:22]([C:24]5[CH:31]=[CH:30][C:27]([CH:28]=O)=[CH:26][CH:25]=5)[S:23][C:16]=34)=[CH:11][CH:12]=2)[CH:7]=[CH:6]1>>[NH:5]1[C:13]2[C:8](=[CH:9][C:10]([NH:14][C:15]3[CH:20]=[CH:19][N:18]=[C:17]4[CH:21]=[C:22]([C:24]5[CH:31]=[CH:30][C:27]([CH2:28][NH:1][CH2:2][CH2:3][OH:4])=[CH:26][CH:25]=5)[S:23][C:16]=34)=[CH:11][CH:12]=2)[CH:7]=[CH:6]1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 183827434-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzaldehyde

Product 1

HCID 183829022-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzylamino}-ethanol

Procedure

The title compound was prepared from 2-aminoethanol and 4-[7-(1H-indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzaldehyde by a procedure analogous to example 17. LC-MS: 415 (MH+); HPLC RT: 3.40 minutes.

Sources & evidence

ORD record
ord-f519034334394d95b8e01a389d0b28f8
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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