6-(Dimethylamino)hexylamine → N-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzyl}-N',N'-dimethyl-hexane-1,6-diamine

HRID 2297804Notes

Reaction equation

HRID 2297804 reaction equation
[CH3:1][N:2]([CH3:10])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][NH2:9].[NH:11]1[C:19]2[C:14](=[CH:15][C:16]([NH:20][C:21]3[CH:26]=[CH:25][N:24]=[C:23]4[CH:27]=[C:28]([C:30]5[CH:37]=[CH:36][C:33]([CH:34]=O)=[CH:32][CH:31]=5)[S:29][C:22]=34)=[CH:17][CH:18]=2)[CH:13]=[CH:12]1>>[NH:11]1[C:19]2[C:14](=[CH:15][C:16]([NH:20][C:21]3[CH:26]=[CH:25][N:24]=[C:23]4[CH:27]=[C:28]([C:30]5[CH:37]=[CH:36][C:33]([CH2:34][NH:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][N:2]([CH3:10])[CH3:1])=[CH:32][CH:31]=5)[S:29][C:22]=34)=[CH:17][CH:18]=2)[CH:13]=[CH:12]1

Participants

3

Reactant 2

HCID 2585446-(Dimethylamino)hexylamineHCID 183827434-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzaldehyde

Product 1

HCID 18382923N-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzyl}-N',N'-dimethyl-hexane-1,6-diamine

Procedure

The title compound was prepared from N,N-dimethyl-hexane-1,6-diamine and 4-[7-(1H-indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzaldehyde by a procedure analogous to example 17. LC-MS: 498 (MH+); HPLC RT: 3.93 minutes.

Sources & evidence

ORD record
ord-c9510cc8411342e2acc83ab7f5a6d918
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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