(Phenylmethoxy)acetaldehyde → HCID 18382855, compound

HRID 2297813Notes

Reaction equation

HRID 2297813 reaction equation
[CH2:1]([O:8][CH2:9][CH:10]=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:12]1([C:18]2[S:26][C:25]3[C:24]([NH:27][C:28]4[CH:33]=[CH:32][C:31]([NH2:34])=[CH:30][CH:29]=4)=[N:23][CH:22]=[N:21][C:20]=3[CH:19]=2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH2:1]([O:8][CH2:9][CH2:10][NH:34][C:31]1[CH:30]=[CH:29][C:28]([NH:27][C:24]2[C:25]3[S:26][C:18]([C:12]4[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=4)=[CH:19][C:20]=3[N:21]=[CH:22][N:23]=2)=[CH:33][CH:32]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 108989(Phenylmethoxy)acetaldehydeHCID 18383034HCID 18383034, compound

Product 1

HCID 18382855HCID 18382855, compound

Procedure

The title compound was prepared from benzyloxy-acetaldehyde (12 mg, 0.079 mmol) and N-(6-Phenyl-thieno[3,2-d]pyrimidin-4-yl)-benzene-1,4-diamine (150 mg, 0.471 mmol) by a procedure analogous to example 17. RP18-HPLC RT: 7.062 minutes; API MS: 452.58 (M+1) MP: 201-203° C.

Sources & evidence

ORD record
ord-26aef5ebb5464831bbbd93dbb295c0ca
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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