(2-Nitrophenyl)boronic acid → HCID 18382819, compound

HRID 2297817Notes

Reaction equation

HRID 2297817 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1B(O)O)([O-:3])=[O:2].Br[C:14]1[S:22][C:21]2[C:20]([NH:23][C:24]3[CH:29]=[CH:28][C:27]([NH:30][C:31]4[CH:36]=[CH:35][C:34]([O:37][CH3:38])=[CH:33][CH:32]=4)=[CH:26][CH:25]=3)=[N:19][CH:18]=[N:17][C:16]=2[CH:15]=1>>[CH3:38][O:37][C:34]1[CH:35]=[CH:36][C:31]([NH:30][C:27]2[CH:26]=[CH:25][C:24]([NH:23][C:20]3[C:21]4[S:22][C:14]([C:5]5[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=5[N+:1]([O-:3])=[O:2])=[CH:15][C:16]=4[N:17]=[CH:18][N:19]=3)=[CH:29][CH:28]=2)=[CH:32][CH:33]=1

Participants

3

Reactant 2

HCID 2773548(2-Nitrophenyl)boronic acidHCID 18382822HCID 18382822, compound

Product 1

HCID 18382819HCID 18382819, compound

Procedure

The title compound was prepared from 2-nitrobenzeneboronic acid and N-(6-Bromo-thieno[3,2-d]pyrimidin-4-yl)-N′-(4-methoxy-phenyl)-benzene-1,4-diamine by a procedure analogous to example 2. M.P. 228-237° C. ; LC-MS: 383.56 (MH+); HPLC RT: 6.885 minutes.

Sources & evidence

ORD record
ord-e282d7aacd8d45e08c5a9ac6690ef253
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

Loading…