4-Formylphenylboronic Acid → HCID 18382870, compound

HRID 2297821Notes

Reaction equation

HRID 2297821 reaction equation
[CH:1]([C:3]1[CH:8]=[CH:7][C:6](B(O)O)=[CH:5][CH:4]=1)=[O:2].Br[C:13]1[S:21][C:20]2[C:15](=[N:16][CH:17]=[CH:18][C:19]=2[NH:22][C:23]2[CH:24]=[C:25]3[C:29](=[CH:30][CH:31]=2)[NH:28][C:27]([CH3:32])=[CH:26]3)[CH:14]=1>>[CH3:32][C:27]1[NH:28][C:29]2[C:25]([CH:26]=1)=[CH:24][C:23]([NH:22][C:19]1[CH:18]=[CH:17][N:16]=[C:15]3[CH:14]=[C:13]([C:6]4[CH:7]=[CH:8][C:3]([CH:1]=[O:2])=[CH:4][CH:5]=4)[S:21][C:20]=13)=[CH:31][CH:30]=2

Participants

3

Reactant 2

HCID 5910734-Formylphenylboronic AcidHCID 183828502-Bromo-N-(2-methyl-1H-indol-5-yl)thieno[3,2-b]pyridin-7-amine

Product 1

HCID 18382870HCID 18382870, compound

Procedure

The title compound was prepared from 4-formylbenzeneboronic acid and (2-bromo-thieno[3,2-b]pyridin-7-yl)-(2-methyl-1H-indol-5-yl)-amine by a procedure analogous to example 17. RP18-HPLC RT: 5.391 minutes; API MS: 384.29 (M+1).

Sources & evidence

ORD record
ord-c66a622555404b6cac11d045f5b5a596
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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