Morpholine → HCID 10434122, compound

HRID 2297823Notes

Reaction equation

HRID 2297823 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([NH:11][C:12]1[CH:17]=[CH:16][N:15]=[C:14]3[CH:18]=[C:19]([C:21]4[CH:28]=[CH:27][C:24]([CH:25]=O)=[CH:23][CH:22]=4)[S:20][C:13]=13)=[CH:6][CH:5]=2.[NH:29]1[CH2:34][CH2:33][O:32][CH2:31][CH2:30]1>>[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([NH:11][C:12]1[CH:17]=[CH:16][N:15]=[C:14]3[CH:18]=[C:19]([C:21]4[CH:28]=[CH:27][C:24]([CH2:25][N:29]5[CH2:34][CH2:33][O:32][CH2:31][CH2:30]5)=[CH:23][CH:22]=4)[S:20][C:13]=13)=[CH:6][CH:5]=2

Participants

3

Reactant 2

HCID 8083MorpholineHCID 18382870HCID 18382870, compound

Product 1

HCID 10434122HCID 10434122, compound

Procedure

The title compound was prepared from 4-[7-(2-methyl-1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzaldehyde(60 mg, 0.156 mmol) and morpholine (82 mg, 0.939 mmol) by a procedure analogous to example 89. RP18-HPLC RT: 4.652 minutes; API MS: 454.59 (M+1).

Sources & evidence

ORD record
ord-6597299e56344ec19b7814070cb5b708
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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