HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-2-methylindole → (2-Methyl-1H-indol-5-yl)-[2-(6-methyl-pyridin-2-yl)-thieno[3,2-b]pyridin-7-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-2-methylindole | HCID 2733992 | — |
| Reactant | 7-Chloro-2-(6-methyl-pyridin-2-yl)-thieno[3,2-b]pyridine | HCID 18382761 | — |
| Product | (2-Methyl-1H-indol-5-yl)-[2-(6-methyl-pyridin-2-yl)-thieno[3,2-b]pyridin-7-yl]-amine | HCID 18382826 | — |
Reaction Steps
The title compound was prepared from 2-methyl-5-aminoindole and 7-chloro-2-(6-methyl-pyridin-2-yl)-thieno[3,2-b]pyridine by the procedure analogous to example 148(c) above. 1H NMR (400 MHz, CD3OD) δ8.51 (d, 1H), 7.83 (s, 1H), 7.68 (m, 2H), 7.34 (m, 1H), 7.27 (d, 1H), 7.16 (d, 1H), 6.97 (dd, 1H), 6.57 (d, 1H), 6.10 (s, 1H), 2.52 (s, 3H), 2.40 (s, 3H); RP18-HPLC RT: 5.70 minutes; API MS: 371 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492383B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-10bb80b965144ea09f6f5414414c6e62 |
| Source note | uspto-grants-2002_12 |