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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2297856Generated: November 1, 2026

5-Amino-2-methylindole → HCID 18382778, compound

https://huagongshe.com/reaction/2297856

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Amino-2-methylindoleHCID 2733992—
ReactantHCID 18382860HCID 18382860—
ProductHCID 18382778HCID 18382778—

Reaction Steps

The title compound was prepared from [6-(7-chloro-thieno[3,2-b]pyridin-2-yl)-pyridin-2-yl]-morpholin-4-yl-methanone and 2-methyl-5-aminoindole by the procedure analogous to example 148(c) above. 1H NMR (400 MHz, CD3OD) δ8.10 (d, 1H), 7.98 (d, 1H), 7.89 (t, 1H), 7.83 (s, 1H), 7.56 (d, 1H), 7.33 (s, 1H), 7.29 (d, 1H), 6.96 (d, 1H), 6.61 (d, 1H), 6.11 (s, 1H), 3.74 (s, 4H), 3.49 (s, 4H), 2.42 (s, 3H); RP18-HPLC RT: 4.58 minutes; API MS: 470 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06492383B1
Source datasetuspto-grants-2002_12
ORD IDord-9676503b821140a1bfa8dde0a2993bab
Source noteuspto-grants-2002_12