Ammonium Hydroxide → 8-amino-1-{4-[(aminothio)peroxy]phenyl}-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide

Participants

Reaction Steps

The product of Example 4a (968 mg), conc. ammonium hydroxide (10 mL), and methanol (5 mL) were heated at 95° C. in a sealed pressure bottle for 16 h. The mixture was allowed to cool and let stand for 3 h. The resulting amber solid was collected by filtration to yield the title compound (630 mg).

Provenance & Evidence