Tetrahydrofuran → HCID 53742797, compound

Participants

Reaction Steps

Prepared as described in Example 5b) using (+/−)-2-chloro-5-[3-[[(1,1-dimethylethoxy)carbonyl]amino]-1-pyrrolidinyl]-benzoic acid, ethyl ester (Example 7a, 0.25 g), lithium hydroxide monohydrate (1.36 ml of a 3M solution in water), 1:1 ethanol/water (7 ml) and tetrahydrofuran (1 ml) to give the subtitle compound as a solid (0.23 g).

Provenance & Evidence