HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → HCID 54311627, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Chloro-2-(diethylamine)ethane hydrochloride | HCID 13363 | — |
| Reactant | HCID 54334627 | HCID 54334627 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 54311627 | HCID 54311627 | — |
Reaction Steps
The methyl ester was prepared via O-alkylation of N-(toluene-4-sulfonyl)-L-prolyl-L-tyrosine methyl ester with 2-diethylaminoethyl chloride hydrochloride in refluxing 2-butanone in the presence of potassium carbonate and sodium iodide. The title compound was prepared using the procedure described in Method 7 as a solid, mp=105-109° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492421B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-231251c0148543a39df41f504dba7320 |
| Source note | uspto-grants-2002_12 |