HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → HCID 70054071, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(2-Chloropropyl)piperidine | HCID 102469 | — |
| Reactant | HCID 54334627 | HCID 54334627 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 70054071 | HCID 70054071 | — |
Reaction Steps
The methyl ester was prepared via O-alkylation of N-(toluene-4-sulfonyl)-L-prolyl-L-tyrosine methyl ester with 1-(2-chloropropyl)piperidine in refluxing 2-butanone in the presence of potassium carbonate and sodium iodide. The title compound was prepared using the procedure described in Method 7 as a solid, mp=122-125° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492421B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-120e0b083ac94461803b507a7997b9f2 |
| Source note | uspto-grants-2002_12 |