1-Naphthaleneboronic acid → HCID 18385681, compound

Participants

Reaction Steps

200 mg of 4bromo-2,2-dimethyl-5-{4-(methylsulfonyl)phenyl}-3(2H)-furanone was coupled with 114 mg of naphthalene-1-boronic acid by a procedure similar to the procedure employed for Example 2 to afford 2,2-dimethyl-5-{4-(methylsulfonyl)phenyl}-4-(1-naphthyl)-3(2H)-furanone as a solid. mp: 194-195° C. NMR: δ1.67 (s, 3H), 1.71 (s, 3H), 2.97 (s, 3H), 7.33-7.43 (m, 2H), 7.48-7.60 (m, 2H), 7.51-7.52 (m, 1H), 7.66-7.69 (m, 2H), 7.76-7.78 (m, 2H), 7.90-7.94 (m, 2H), IR (cm−1): 1698, 1404, 1318, 1149, 1092, 772.

Provenance & Evidence