(2H-1,3-benzodioxol-5-yl)boronic acid → HCID 18386024, compound

Participants

Reaction Steps

120 mg of 5-{4-(aminosulfonyl)phenyl}-2,2-dimethyl-4-iodo-3(2H)-furanone was reacted with 100 mg of 3,4-(methylenedioxy)benzeneboronic acid by following a procedure similar to Step 4 of Example 22 to yield 40 mg of 5-{4-(aminosulfonyl)phenyl}-2,2-dimethyl-4-{3,4-(methylenedioxy)phenyl}-3(2H)-furanone as a solid. mp: 178-179° C. NMR: δ1.56 (s, 6H), 4.89 (br s, 2H), 5.99 (s, 2H), 6.74 (m, 2H), 6.83 (m, 1H), 7.82 (d, J=9.0 Hz, 2H), 7.92 (d, J=9.0 Hz, 2H). IR (cm−1): 3237, 1682, 1338, 1245, 1164.

Provenance & Evidence