Phenylboronic Acid → HCID 18385854, compound

Participants

Reaction Steps

100 mg of 5-{4-(aminosulfonyl)phenyl}-2-ethyl-4-iodo-2-methyl-3(2H)-furanone was reacted with 90 mg of benzeneboronic acid by following a procedure similar to Step 2 of Example 35 to give 30 mg of 5-{4-(aminosulfonyl)phenyl}-2-ethyl-2-methyl-4-phenyl-3(2H)-furanone as a solid. mp: 153-154° C. NMR: δ0.95 (t, J=7.5 Hz, 3H), 1.54 (s, 3H), 1.97 (m, 2H), 4.89 (br s, 2H), 7.26 (m, 2H), 7.36 (m, 3H), 7.79 (d, J=8.7 Hz, 2H), 7.90 (d, J=8.7 Hz, 2H). IR (cm−1): 3340, 3256, 1684, 1616, 1392, 1342, 1161.

Provenance & Evidence