2-Methoxythiophene → HCID 69975430, compound

HRID 2298349Notes

Reaction equation

HRID 2298349 reaction equation
[CH3:1][O:2][C:3]1[S:4][CH:5]=[CH:6][CH:7]=1.[ClH:8].[N:9]12[CH2:16][CH2:15][CH:12]([CH2:13][CH2:14]1)[C@@H:11]([NH:17][C:18](C1SC(C#N)=CC=1)=[O:19])[CH2:10]2>>[ClH:8].[N:9]12[CH2:16][CH2:15][CH:12]([CH2:13][CH2:14]1)[C@@H:11]([NH:17][C:18]([C:5]1[S:4][C:3]([O:2][CH3:1])=[CH:7][CH:6]=1)=[O:19])[CH2:10]2

Participants

3

Reactant 2

HCID 856102-MethoxythiopheneHCID 69975145HCID 69975145, compound

Product 1

HCID 69975430HCID 69975430, compound

Procedure

This compound is prepared from 2-methoxythiophene according to the procedure used to make the compound of Example 18, making noncritical variations. Yield for 2 steps 33%. mRMS (FAB) calculated for C13H18N2O2S+H 267.1167, found 267.1167.

Workup

  1. customYield for 2 steps 33%

Sources & evidence

ORD record
ord-32a331827d4f43feaa5141301c1ed68e
Source dataset
uspto-grants-2002_12
Patent number
US06492385B2

Reaction notes

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