HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromobutyric acid → tert-Butyl 4-bromobutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromobutyric acid | HCID 75809 | — |
| Reactant | Tert-butyl 6-bromohexanoate | HCID 11550568 | — |
| Solvent | Isobutylene | HCID 8255 | — |
| Product | tert-Butyl 4-bromobutanoate | HCID 2757253 | 54% |
Reaction Steps
4-Bromobutanoic acid (8 g, 47.9 mmol) and iso-butene (60 ml) were reacted by the same procedure as described in Example 1 for the preparation of tert-butyl 6-bromohexanoate to give the title material (5.7 g, 54%) as a colorless liquid (b.p. 62-64° C./10 mmHg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492550B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-6a79c0c2e4344e49b1f5ccc44def3706 |
| Source note | uspto-grants-2002_12 |