HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium triacetoxyborohydride → HCID 18338589, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | HCID 18338590 | HCID 18338590 | — |
| Reactant | HCID 18338591 | HCID 18338591 | — |
| Product | HCID 18338589 | HCID 18338589 | 78.2% |
Reaction Steps
Crude methyl 5-tert-butoxycarbonyl-2-oxopentanoate (1.08 g, 4.7 mmol) and sodium triacetoxyborohydride (1.0 g, 4.7 mmol) were reacted by the same procedure as described in Example 1 for the preparation of methyl 7-tert-butoxycarbonyl-2-hydroxyheptanoate to give the title compound (854 mg, 78%, 2 steps) as a colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492550B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-e3099403744d498da84b38d55f7c3a26 |
| Source note | uspto-grants-2002_12 |