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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2298583Generated: October 29, 2026

2-Bromo-1-(3,4-dichlorophenyl)ethanone → HCID 86758664, compound

https://huagongshe.com/reaction/2298583

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1-(3,4-dichlorophenyl)ethanoneHCID 244751—
ReactantMethyl 4-(aminothioxomethyl)-5-methylthiothiophene-2-carboxylateHCID 86583815—
ProductHCID 86758664HCID 8675866494.7%

Reaction Steps

176 mg (0.712 mmol) of methyl 4-(aminothioxomethyl)-5-methylthiothiophene-2-carboxylate (Maybridge Chemical Co. LTD., Cornwall, U.K.) was reacted with 2-bromo-3′,4′-dichloroacetophenone (0.854 mmol; 330 mg) in a manner similar to Example 22, step (a) to afford 270 mg (91% yield) of methyl 4-[4-(3,4-dichlorophenyl)(1,3-thiazol-2-yl)]-5-methylthiothiophene-2-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06492403B1
Source datasetuspto-grants-2002_12
ORD IDord-ff4ad753b87c4be1a393dd072d8ac06e
Source noteuspto-grants-2002_12