HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-2'-methylacetophenone → HCID 86758666, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-2'-methylacetophenone | HCID 12430676 | — |
| Reactant | Methyl 4-(aminothioxomethyl)-5-methylthiothiophene-2-carboxylate | HCID 86583815 | — |
| Product | HCID 86758666 | HCID 86758666 | 55.5% |
Reaction Steps
160 mg (0.647 mmol) of methyl 4-(aminothioxomethyl)-5-methylthiothiophene-2-carboxylate (Maybridge Chemical Co. LTD., Cornwall, U.K.) was reacted with 2-bromo-2′-methyl acetophenone (0.711 mmol, 152 mg) in a manner similar to Example 22, step (a) to afford 124 mg (53% yield) of methyl 4-[4-(2-methylphenyl)(1,3-thiazol-2-yl)]-5-methylthiothiophene-2-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492403B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-88b1d110adac4376a384630222f2e53a |
| Source note | uspto-grants-2002_12 |