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HRID229873

反应详情

EQUATION

反应方程式

HRID 229873 的结构方程式

REACTANTS

反应物

4
结构：COC(=O)CC(C)=O
HCID7757

Methyl acetoacetate

C5H8O3

结构：N[C@@H]1CCCC[C@H]1O
HCID735777

(1R,2R)-2-Aminocyclohexanol

C6H13NO

结构：O=C(CBr)c1cc(C(F)(F)F)ccc1F
HCID2778784

2-Bromo-1-[2-fluoro-5-(trifluoromethyl)phenyl]ethan-1-one

C9H5BrF4O

结构：CC1(C)OCC(CN)O1
HCID4122349

(2,2-dimethyl-1,3-dioxolan-4-yl)methanamine

C6H13NO2

PRODUCTS

生成物

1
结构：Cc1c(C(=O)N[C@@H]2CCCC[C@H]2O)cc(-c2cc(C(F)(F)F)ccc2F)n1CC1COC(C)(C)O1
HCID11656235

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to example 7, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-[2-fluoro-5-(trifluoromethyl)-phenyl]-ethanone as compound of formula S, 2,2-dimethyl-1,3-dioxolan-4-methylamine as R3—(CH2)m—NH2 and (1R,2R)-2-aminocyclohexanol as R1R2NH, MS (ISP) 499.5 (M+H)+.