Hexyl isocyanate → HCID 59924188, compound

Participants

Reaction Conditions

Reaction Steps

(2R)-2-amino-2-phenylethanol (960 mg) was dissolved in methylene chloride (20 ml) and cooled to 0° C. To the mixture was added hexyl isocyanate (1.0 ml) and the mixture was stirred for 30 minutes at 0° C. and then stirred for 1 hour at room temperature. The solution was washed with 1N hydrochloric acid and a saturated aqueous solution of sodium chloride, successively, dried and concentrated under reduced pressure. The obtained crystal was washed with diethyl ether to give the title compound (930 mg) having the following physical data.

Provenance & Evidence