反应详情

Under a hydrogen pressure of 45 psi, 17.70 g (91.7 mmol) of the compound obtained in Step A and 2.5 g of palladium-on-carbon suspended in 300 ml of ethanol are stirred for 5 hours at room temperature. After filtration over Celite and evaporation, the residue is purified over silica gel (eluant: petroleum ether/ethyl acetate, 4:1) to yield the title product in the form of a brown solid.

1. filtrationAfter filtration
2. customover Celite and evaporation
3. customthe residue is purified over silica gel (eluant: petroleum ether/ethyl acetate, 4:1)