反应详情

Under a hydrogen pressure of 45 psi, 510 mg (1.63 mmol) of the compound obtained in Step C and 72 mg of palladium-on-carbon suspended in 10 ml of methanol are stirred for 15 hours at room temperature. After filtration over Celite and evaporation, the residue is hydrolysed with water and then extracted with ethyl acetate. The organic phase is dried over magnesium sulphate and evaporated to yield the title compound in the form of a brown solid.

1. filtrationAfter filtration
2. customover Celite and evaporation
3. extractionextracted with ethyl acetate
4. dry with materialThe organic phase is dried over magnesium sulphate
5. customevaporated