Bromine → 2-Bromohypoxanthine

HRID 2298780Notes

Reaction equation

HRID 2298780 reaction equation
[NH:1]1[C:10](=[O:11])[C:9]2[NH:8][CH:7]=[N:6][C:5]=2[NH:4][C:2]1=S.[Br:12]Br>>[Br:12][C:2]1[NH:1][C:10](=[O:11])[C:9]2[NH:8][CH:7]=[N:6][C:5]=2[N:4]=1

Participants

3

Reactant 2

HCID 24408BromineHCID 12681852-Thioxanthine

Product 1

HCID 1354139912-Bromohypoxanthine

Procedure

This compound is prepared from 2-thioxanthine** through oxidation of the mercapto group by bromine and in situ displacement by hydrobromine. For reference on the oxidation and displacement, see Beaman, A. G.; Gerster, J. F.; Robins, R. K, J. Org. Chem, 1962, 27, 986.1.

Sources & evidence

ORD record
ord-8d487994f1ae4342af2236d715415f6d
Source dataset
uspto-grants-2002_12
Patent number
US06495528B1

Reaction notes

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