Sodium borohydride → HCID 9825971, compound

Participants

Reaction Steps

To an ice-bath-cooled solution of 2-methoxy-N-(2-methyl-1H-benzimidazol-4-yl) -4-(2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonylbenzamide (123 mg) in methanol (5 ml) was added sodium borohydride (10 mg), and the mixture was stirred at the same temperature for 1 hour. The reaction mixture was diluted with chloroform and the solution was washed with water and brine. The solution was dried over magnesium sulfate and the solvent was evaporated in vacuo. The residue was triturated with ether to give 2-methoxy-N-(2-methyl-1H-benzimidazol-4-yl)-4-(2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonylbenzamide (123 mg).

Provenance & Evidence