HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → (2S)-1-(5-chloro-1,3-benzoxazol-2-yl)-2-piperidinecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | benzyl(2S)-1-(5-chloro-1,3-benzoxazol-2-yl)-2-piperidinecarboxylate | HCID 53932308 | — |
| Product | (2S)-1-(5-chloro-1,3-benzoxazol-2-yl)-2-piperidinecarboxylic acid | HCID 53730159 | — |
Reaction Steps
The title compound was prepared by a similar method to Preparation 3 from benzyl (2S)-1-(5-chloro-1,3-benzoxazol-2-yl)-2-piperidinecarboxylate [see Preparation 28] and 1N aqueous lithium hydroxide solution to afford (2S)-1-(5-chloro-1,3-benzoxazol-2-yl)-2-piperidinecarboxylic acid as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495549B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-67364bf7592547858a01770e8c202c21 |
| Source note | uspto-grants-2002_12 |