HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 15871164, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 15895806 | HCID 15895806 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 15871164 | HCID 15871164 | — |
Reaction Steps
At 0°, 1 equivalent of DMF and 1 equivalent of oxalyl chloride are dissolved in acetonitrile. 1 equivalent of 3-[4-(3-chloro-4-methoxybenzylamino)-benzothieno[2,3-d]pyrimidin-2-yl]propionamide is then added. The mixture is stirred for one hour. Customary work-up gives 3-[4-(3-chloro-4-methoxybenzylamino)benzothieno[2,3-d]pyrimidin-2-yl]propionitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495557B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-76a8b39992ab426f9b2460f38d598337 |
| Source note | uspto-grants-2002_12 |