2-Chloro-3-pyridylamine → 3-(2-Chloro-pyridin-3-ylamino)-4-ethoxy-cyclobut-3-ene-1,2-dione

HRID 2299065Notes

Reaction equation

HRID 2299065 reaction equation
[Cl:1][C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][N:3]=1.[CH2:9]([O:11][C:12]1[C:13](=O)[C:14](=[O:19])[C:15]=1[O:16]CC)[CH3:10]>C(O)C>[Cl:1][C:2]1[C:7]([NH:8][C:13]2[C:14](=[O:19])[C:15](=[O:16])[C:12]=2[O:11][CH2:9][CH3:10])=[CH:6][CH:5]=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 805282-Chloro-3-pyridylamineHCID 123228Diethyl squarate

Product 1

HCID 108247303-(2-Chloro-pyridin-3-ylamino)-4-ethoxy-cyclobut-3-ene-1,2-dione

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 2-chloro-3-aminopyridine and 3,4-diethoxy-3-cyclobutene-1,2-dione in ethanol was processed as described in Example 1A to provide the title compound.

Sources & evidence

ORD record
ord-057f1e9803424637900df4a3e597884c
Source dataset
uspto-grants-2002_12
Patent number
US06495576B2

Reaction notes

Loading…