Aminopyrazine → HCID 18379727, compound

HRID 2299091Notes

Reaction equation

HRID 2299091 reaction equation
[NH2:1][C:2]1[CH:7]=[N:6][CH:5]=[CH:4][N:3]=1.[CH2:8]([O:10][C:11]1[C:12](=O)[C:13](=[O:18])[C:14]=1[O:15]CC)[CH3:9]>C(O)C>[CH2:8]([O:10][C:11]1[C:14](=[O:15])[C:13](=[O:18])[C:12]=1[NH:1][C:2]1[CH:7]=[N:6][CH:5]=[CH:4][N:3]=1)[CH3:9]

Participants

4

Reactant 2

HCID 78747AminopyrazineHCID 123228Diethyl squarate

Product 1

HCID 18379727HCID 18379727, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of aminopyrazine and 3,4-diethoxy-3-cyclobutene-1,2-dione in ethanol was processed as described in Example 1A to provide the title compound. MS (DCI/NH3) m/z 220 (M+H)+.

Sources & evidence

ORD record
ord-3e3c58ebfffa4a68aa8acacc3253a3dc
Source dataset
uspto-grants-2002_12
Patent number
US06495576B2

Reaction notes

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