Benzamide → N-[1-(1H-1,2,3-benzotriazol-1-yl)-3,3-dimethylbutyl]benzamide
Reaction equation
[C:1]([NH2:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:10][C:11]([CH3:16])([CH3:15])[CH2:12][CH:13]=O.[NH:17]1[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[N:19]=[N:18]1>>[N:17]1([CH:13]([NH:9][C:1](=[O:8])[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH2:12][C:11]([CH3:16])([CH3:15])[CH3:10])[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[N:19]=[N:18]1Participants
4
Procedure
A suspension of benzamide, 3,3-dimethyl-butyraldehyde, and benzotriazole were processed as described in Example 18B to provide the desired product.
Sources & evidence
- ORD record
- ord-6f7d72a088ef47a6963a206632ddd91c
- Source dataset
- uspto-grants-2002_12
- Patent number
- US06495576B2
Reaction notes
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