HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 18379811, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | HCID 18379880 | HCID 18379880 | — |
| Reactant | Dichloromethane methanol | HCID 21226129 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 18379811 | HCID 18379811 | 50% |
Reaction Steps
To a solution of 3-cyclopentyl-5-aminobenzimidazole (1.0 g, 5.0 mmol) in 20 ml of AcOH was added solution of Br2 in AcOH until it produces a precipitation. The reaction mixture was concentrated in vacuo to provide a brown solid which was subjected to column chromatography (5% NH3 sat'd MeOH/CH2Cl2) to provide 0.70 g (2.5 mmol, 50%) of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495583B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-a97f3667035a4a4b8eccae3a2421db28 |
| Source note | uspto-grants-2002_12 |