Bromine → HCID 178437480, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 1.3 g (7.7 mmol) of 2-ethyl-5-aminobenzimidazole in 50 ml of AcOH was added 0.40 ml of Br2 (7.5 mmol) dropwise and resulting reaction mixture was stirred for 1 h at 25° C. The reaction mixture was concentrated in vacuo and purified on silica gel column chromatography (20% isopropanol /EtOAC) to yield 1.5 g (6.3 mmol, 82%) of the desired product.

Provenance & Evidence