Acetone → HCID 18380106, compound

HRID 2299229Notes

Reaction equation

HRID 2299229 reaction equation
[SH:1][CH2:2][C:3]([CH2:5][SH:6])=[CH2:4].[CH3:7][C:8]([CH3:10])=O.[Cl-].[Al+3].[Cl-].[Cl-].O>ClCCl>[CH3:7][C:8]1([CH3:10])[S:6][CH2:5][C:3](=[CH2:4])[CH2:2][S:1]1

Participants

6

Reactant 4

HCID 180AcetoneHCID 962WaterHCID 6451240Aluminum(III) ChlorideHCID 15271515HCID 15271515, compound

Product 1

HCID 18380106HCID 18380106, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-(Mercaptomethyl)-3-mercapto-1-propene (Z. Chem. 1975, 15, 302)(0.83 g, 6.9 mmoles) and acetone (0.51 mL) were placed in about 15 mL of dichloromethane. Then anhydrous aluminum chloride (0.32 g) was added portionwise over one minute at room temperature. The solution was stirred at room temperature for 30 minutes. The reaction was worked up by addition of 20 mL of water followed by extraction with dichloromethane. The extracts were dried and evaporated to give 0.89 g clear oil with a penetrating smell. The oil was chromatographed to give 400 mg (40%) of clear oil.

Workup

  1. extractionfollowed by extraction with dichloromethane
  2. customThe extracts were dried
  3. customevaporated

Sources & evidence

ORD record
ord-6589964ea9f143ebbbfb584887f0e99a
Source dataset
uspto-grants-2002_12
Patent number
US06495643B1

Reaction notes

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