Water → 23133-34-8

Participants

Reaction Conditions

Reaction Steps

3.5 g (13.89 mmol) of 2-(p-anisoyl) 5-phenyl 1,3,4-oxadiazole and 100 mL of concentrated HI aqueous solution was mixed under nitrogen and refluxed at 130° C. for 12 hours. The mixture was cooled down to room temperature and 100 mL of deionized water was added. The precipitate was collected by filtration and dried under vacuum, p-(5-phenyl-1,3,4-oxadiazole-2-yl)phenol was obtained. 1H-NMR (acetone-d6, ppm): δ 9.26 (s, 1H), δ 8.15 (m, 2H), δ 8.06 (d, 2H), δ 7.62 (m, 3H), δ 7.07 (d, 2H); mp 256.5° C.

Provenance & Evidence