Ammonia → 2,3,5-Trimethylpyridine

Participants

Reaction Steps

A process comprising reacting methacrolein with ammonia in a gas phase in the presence of a catalyst which comprises silicon and an element such as zirconium, aluminium and/or phosphorus (see JP-A-8-245589), and a process comprising reacting methacrolein and methyl ethyl ketone with ammonia in a gas phase in the presence of an oxide catalyst comprising silicon, phosphorus and/or boron (see JP-A-8-259537). However, the main product of the former process is 3,5-lutidine, while 2,3,5-collidine is obtained in a yield of only 16.5%. In the latter process, 2,3,5-collidine is obtained in a yield of 15 to 37%.

Provenance & Evidence