HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 22568804, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(2-Methyl-4-trimethylsilanylethynyl-benzyl)-1H-imidazole | HCID 22568964 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22568804 | HCID 22568804 | — |
Reaction Steps
Using General Procedure E; 1-(2-methyl-4-trimethylsilanylethynyl-benzyl)-1H-imidazole (Intermediate 140, 140.0 mg, 0.53 mmols) in methanol (5 mL) was treated with potassium carbonate (100.0 mg, 0.72 mmol) and stirred overnight at ambient temperature. The crude alkyne (105 mg, 100%) was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495552B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-a05aa46b09794353bad6b2766e965224 |
| Source note | uspto-grants-2002_12 |