HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl (2S)-2-aminopentanoate hydrochloride → N-[N-(3,5-dichlorophenyl)-L-alanyl]-(S)-2-aminopentanoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl (2S)-2-aminopentanoate hydrochloride | HCID 14118488 | — |
| Reactant | N-(3,5-dichlorophenyl)-D,L-alanine | HCID 15484844 | — |
| Product | N-[N-(3,5-dichlorophenyl)-L-alanyl]-(S)-2-aminopentanoic acid methyl ester | HCID 54555894 | — |
Reaction Steps
Following General Procedure D and using N-(3,5-dichlorophenyl)-D,L-alanine (from Example B above) and L-norvaline methyl ester hydrochloride (Sennchem), the title compound was prepared. The reaction product was purified by silica gel chromatography using 50% ethyl acetate/hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495693B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-6580659cad7d47f68d6952bc89f7d19e |
| Source note | uspto-grants-2002_12 |