HuagongsheHuagongshe Chemistry Print Report · For research reference only
Leucinamide hydrochloride → N-[N-(3,4-dichlorophenyl)-L-alanyl]-L-leucine amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Leucinamide hydrochloride | HCID 2733199 | — |
| Reactant | 2-(3,4-Dichloro-phenylamino)-propionic Acid | HCID 6916426 | — |
| Product | N-[N-(3,4-dichlorophenyl)-L-alanyl]-L-leucine amide | HCID 131721930 | — |
Reaction Steps
Following General Procedure D and using L-leucinamide hydrochloride (Sigma) and N-(3,4-dichlorophenyl)-D,L-alanine (from Example A above), the title compound was prepared. This compound was then purified by column chromatography, eluted first with 1:1 EtOAc/hexane, then with 5% MeOH in methylene chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495693B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-668fd6c6dc1c48f9a0e4a10c089d4849 |
| Source note | uspto-grants-2002_12 |