Phenylalanine amide → HCID 18341182, compound

HRID 2299549Notes

Reaction equation

HRID 2299549 reaction equation
[NH2:1][C@H:2]([C:10]([NH2:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[Cl:13][C:14]1[CH:15]=[C:16]([NH:21][CH:22]([C:24](O)=[O:25])[CH3:23])[CH:17]=[CH:18][C:19]=1[Cl:20]>>[Cl:13][C:14]1[CH:15]=[C:16]([NH:21][CH:22]([C:24]([NH:12][C:10](=[O:11])[C@H:2]([CH2:3][C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)[NH2:1])=[O:25])[CH3:23])[CH:17]=[CH:18][C:19]=1[Cl:20]

Participants

3

Reactant 2

HCID 445694Phenylalanine amideHCID 69164262-(3,4-Dichloro-phenylamino)-propionic Acid

Product 1

HCID 18341182HCID 18341182, compound

Procedure

Following General Procedure D and using phenylalanine amide (Bachem) and N-(3,4-dichlorophenyl)-D,L-alanine (from Example A above), the title compound was prepared as a solid (mp=177-179° C.). This compound was then purified by trituration with chloroform.

Workup

  1. customThis compound was then purified by trituration with chloroform

Sources & evidence

ORD record
ord-13adfdfdd4794c36b5b9aa39b1b51c71
Source dataset
uspto-grants-2002_12
Patent number
US06495693B2

Reaction notes

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