HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → 3-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 3-Nitro-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-5-one | HCID 344487 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one | HCID 266807 | 101.3% |
Reaction Steps
A mixture of 3-nitro-6,7,8,9-tetrahydrobenzocyclohepten-5-one (14.87 g), iron (14.87 g) and ammonium chloride (2.0 g) in ethanol (200 ml) and water (40 ml) was refluxed for 5 hours, and filtered. The filtrate was evaporated in vacuo to afford 3-amino-6,7,8,9-tetrahydrobenzocyclohepten-5-one (12.86 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06495546B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-74352120558a48d49f1648b44b17d620 |
| Source note | uspto-grants-2002_12 |