HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromothiophene-2-carbonitrile → HCID 23435613, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromothiophene-2-carbonitrile | HCID 14292355 | — |
| Reactant | 2-methyl-6-bromospiro[4H-3,1-benzoxazine-4,1'-cyclohexane] | HCID 23435586 | — |
| Product | HCID 23435613 | HCID 23435613 | — |
Reaction Steps
Prepared according to the procedure for Example 13 from 2-methyl-6-bromospiro[4H-3,1-benzoxazine-4,1′-cyclohexane] and 4-bromo-2-thiophenecarbonitrile. A brown solid: mp 111-112° C.; 1H-NMR (DMSO-d6) δ 8.42 (s, 1H), 8.14 (s, 1H), 7.47 (s, 1H), 7.35 (dd, 1H, J=8.3, 1.1 Hz), 6.58 (d, 1H, J=8.4 Hz), 6.38 (s, 1H), 4.72 (m, 1H), 1.92-2.16 (m, 2H), 1.35-1.75 (m, 8H), 1.31 (d, 3H, J=5.3 Hz); MS (ESI) m/z 325 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06498154B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-4b48ccc791cc4c4eac70d38835be2fce |
| Source note | uspto-grants-2002_12 |