Ammonium formate → HCID 10142908, compound

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Reaction Steps

To a solution of 1-{Benzyl-[1-(4-butoxy-benzenesulfonyl)-azetidin-3-yl]-amino}-3-(9H-carbazol-4-yloxy)-propan-2-ol (0.18 g, 0.3 mmol) in methanol (6 ml) was added ammonium formate (0.29 g, 4.5 mmol), and 0.045 g of 10% Pd/C. The mixture was stirred at reflux for 18 h. After cooling to room temperature, it was filtered through Celite. The solvent was evaporated and the residue triturated with isopropyl ether to give 0.14 g of a white solid; m.p. 81-84° C.; MS (ES) m/z 524.0 (MH+); HRMS (ES) Calcd. for C28H34N3O5S (MH+): 524.2219, Found: 524.2252.

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