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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300308Generated: October 31, 2026

Ethyl 2-chloroisonicotinate → Ethyl 2-(4-chloro-3,5-dimethoxyphenyl)isonicotinate

https://huagongshe.com/reaction/2300308

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-chloroisonicotinateHCID 2762942—
Reactant(4-Chloro-3,5-dimethoxyphenyl)boronic acidHCID 22485557—
ProductEthyl 2-(4-chloro-3,5-dimethoxyphenyl)isonicotinateHCID 22557799—

Reaction Steps

4-Chloro-3,5-dimethoxyphenylboronic acid (7.45 g) and ethyl 2-chloroisonicotinate (6.39 g) were condensedn in the same manner as described in Preparation Example 1 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498169B1
Source datasetuspto-grants-2002_12
ORD IDord-7b397530bc2549ecb053fa99bf666b21
Source noteuspto-grants-2002_12