Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300319Generated: November 2, 2026

Ethyl 5-bromopyridine-3-carboxylate → Ethyl 5-(3,4,5-trimethoxyphenyl)nicotinate

https://huagongshe.com/reaction/2300319

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-bromopyridine-3-carboxylateHCID 140785—
Reactant3,4,5-Trimethoxybenzeneboronic acidHCID 2734390—
ProductEthyl 5-(3,4,5-trimethoxyphenyl)nicotinateHCID 22557861—

Reaction Steps

3,4,5-Trimethoxyphenylboronic acid (6.36 g) and ethyl 5-bromonicotinate (6.90 g) were reacted in the same manner as described in Preparation Example 1 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498169B1
Source datasetuspto-grants-2002_12
ORD IDord-81734ea6e4824876875a4a8b307d0237
Source noteuspto-grants-2002_12